“the system for risk assessing chemicals is suitable only for one substance at a time. There is, therefore, no approved method for making an overall assessment of the effect of multiple chemicals simultaneously, i.e. the possibility that chemicals interact with one another to give a stronger or weaker effect than they would have individually. This is commonly called the “combination effect” or popularly known as the “cocktail effect”….
Given how little we currently know about the combination effects of all the different chemical substances that people are exposed to in their day-to-day lives, it may be wise to apply a principle of caution in this regard.”
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